The safety of the veterinary medicinal product has not been established during pregnancy and lactation or in breeding dogs. Laboratory studies in rats and rabbits have not produced any evidence of teratogenic effects, or any adverse effect on the reproductive capacity of males and females. very rare (less than 1 animal in 10,000 animals, including isolated reports).rare (more than 1 but less than 10 animals in 10,000 animals).uncommon (more than 1 but less than 10 animals in 1,000 animals).common (more than 1 but less than 10 animals in 100 animals).very common (more than 1 in 10 animals displaying adverse reactions during the course of one treatment).The frequency of adverse reactions is defined using the following convention: Most reported adverse reactions were self-limiting and of short duration. Mild gastrointestinal effects (vomiting, diarrhoea), pruritus, lethargy, or anorexia and neurological signs (convulsions, ataxia and muscle tremors) have been reported very rarely. Return the blister with the remaining chewable tablets into the carton. To prevent children from getting access to the product, remove only one chewable tablet at a time from the blister. Special precautions to be taken by the person administering the product to animals In the absence of available data, treatment of puppies less than 8 weeks of age and/or dogs less than 2 kg bodyweight should be based on a benefit-risk assessment by the responsible veterinarian. Parasites need to start feeding on the host to become exposed to afoxolaner therefore the risk of the transmission of parasite borne diseases cannot be excluded. canis).ĭo not use in cases of hypersensitivity to the active substance or to any of the excipients. Treatment of sarcoptic mange (caused by Sarcoptes scabiei var. Treatment of demodicosis (caused by Demodex canis). One treatment kills ticks for up to one month.įleas and ticks must attach to the host and commence feeding in order to be exposed to the active substance. Treatment of tick infestation in dogs ( Dermacentor reticulatus, Ixodes ricinus, Rhipicephalus sanguineus). The product can be used as part of a treatment strategy for the control of Flea Allergy Dermatitis (FAD). Treatment of flea infestation in dogs ( Ctenocephalides felis and C.

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